A Randomized-Controlled Trial of Transference-Focused Psychotherapy vs. Treatment by Experienced Community Psychotherapists for Borderline Personality Disorder
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 104
- 试验地点
- 4
- 主要终点
- Drop-out
研究概览
简要总结
The purpose of this study is to find out whether Transference-Focused Psychotherapy (TFP) is effective in the treatment of Borderline Personality Disorder.
详细描述
Borderline personality disorder represents a sever clinical condition that affects 1-2% of the community and is characterized by a pervasive instability of interpersonal relationships, self-image, and affects, as well as a marked impulsivity; up to 10% of the patients commit suicide.
Transference-Focused Psychotherapy (TFP) is one psychotherapeutic approach among five that have been manualized and evaluated in RCTs. So far, TFP has not been compared to a control condition which is a crucial step in the evaluation of the efficacy of a psychosocial intervention.
This study is an RCT that compares one year of outpatient TFP to treatment by experienced community psychotherapists for borderline personality disorder.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Written informed consent to the participation in the study
- •Diagnosis of BPD according to DSM-IV as assessed using the SCID-II
- •Age between 18 and 45 years
- •Sufficient knowledge of the German language
排除标准
- •Diagnosis of schizophrenia, bipolar disorder, severe substance abuse, organic pathology, or mental retardation according to DSM-IV as assessed using the SCID-I
- •Diagnosis of antisocial personality disorder according to DSM-IV as assessed using the SCID-II
结局指标
主要结局
Drop-out
时间窗: 1 year
Did not finish one year of treatment.
Suicidality (Suicide Attempts)
时间窗: 1 year
次要结局
- Psychosocial Functioning (Global Assessment of Functioning, GAF-Score)(1 year)
- Level of Personality Organization (Structured Interview for Personality Organization, STIPO)(1 year)
- Number of Self-harming Acts(1 year)
- Attachment Style and Reflective Function (Adult Attachment Interview, AAI)(1 year)
- Borderline Symptomatology (DSM-IV Criteria)(1 month)
- Self-assessment of Psychopathology (BDI, STAI, BSI)(1 year)
研究者
doerings
Univ.-Prof. Dr. med.
University Hospital Muenster