KCT0002600招募中未知
A Randomized Controlled Trial comparing L-Thyroxine plus Liothyronine with L-thyroxine alone in post-surgical hypothyroidism
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 20(Year) 至 65(Year)（—）
- 性别
- Female
入选标准
- •s/p Total thyroidectomy d/t thyroid cancer
- •Postoperative period 2yr-10yr
- •no evidence of residual disease : non-stimulated Tg <0.2 ng/mL, US (-)
- •Normalized thyroid function (TSH 0.1-5.0 mIU/L) with daily T4 dose ranging from 85.7mcg -150mcg
- •: stable thyroid function in repeated thyroid function test over 6 months interval
- •one of subjective persistent symptoms below compared to preoperative period [1]
- •fatigue or lethargic (0-4)
- •body weight gain (0-4)
- •generalized body pain or ache (0-4)
- •clumsiness (0-4)
- •?(These symptoms should be persistent at least 6 months recently.
- •?Patients with scores = 2 for one of each symptom considered to have subjective symptoms.)
排除标准
- •Person who can not fill in the questionnaire by oneself
- •Uncontrolled heart/liver/kidney disease, anemia (Hb <11)
- •Psychiatric ds/mood disorder
- •Other cancers, DM on insulin injection, dyslipidemia on statin
- •Previous history of combination therapy, within 1 year
- •Underlying autoimmune thyroid ds (TPO+ or lymphocytic thyroiditis in pathology)
研究者
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