Anatomical-Clinical Base of Adenocarcinoma Pancreatic
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,500
- 试验地点
- 8
- 主要终点
- Enrichment of prospective BACAP collection
研究概览
简要总结
BACAP-2 is a prospective biobank dedicated to the pancreatic adenocarcinoma including clinical data and biological samples from tumor. The aim is to enrich the previous propective collection BACAP in order to support future research projects.
详细描述
Pancreatic cancer represents the fourth cause of death by cancer in Western countries. In over 90% of cases, it is due to an adenocarcinoma. The only curative treatment for pancreatic cancer remains the surgical exeresis. This one can only be suggested as a curative treatment in only 10 to 15% of cases. Besides, prevention or screening is difficult to set up due to the absence of clearly identified risk factors or groups and to the absence of useful markers for the diagnosis in clinical practice.
The research efforts in this area must face a double challenge: saving time while improving the diagnosis period and strengthen the therapeutic equipment. It is important to identify and characterise the new molecular markers applicable for a better diagnosis and/or treatment (especially the response factors to chemotherapy).
The present project aims to enrich with fresh tumor tissue and somatic genetic analysis the existing propective collection BACAP in order to support support future research projects on:
- the development of new diagnostic tools,
- understanding the development of tumors of the pancreas
- the development of new therapeutic targets
- understanding the response to chemotherapy...
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 120 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient with pancreatic mass syndrome explored by ultrasound endoscopy with cytopuncture or
- •Patient with pancreatic mass syndrome explored by an abdominal scanner with and without injection of product contrast and/or puncture of the mass or secondary lesions by radiological route or
- •Patient with pancreatic adenocarcinoma proven histologically and/or cytologically
排除标准
- •Patient with a pancreatic tumor whose analysis histological is not an adenocarcinoma
- •Pregnant or breastfeeding patient
结局指标
主要结局
Enrichment of prospective BACAP collection
时间窗: 5 years
This collection is coming to enrich the prospective BACAP collection of fresh tumor tissue and/or fixed from the micro-biopsy under endoscopic ultrasound
次要结局
未报告次要终点