NCT05439369Unknown不适用
Natriuretic Peptides as a Prognostic and Risk Stratification Tool in Assessment of Valvular Heart Disease
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- early detection of subclinical LV dysfunction.
研究概览
简要总结
NPs can be used To detect subset of asymptomatic with subtle LV dysfunction for further evaluation and earlier referral for intervention and its correlation with echocardiographic finding.
详细描述
Each patient included in the study will undergo:
- History taking:
Analysis of patient symptoms and signs (dyspnea , orthopnea , Paroxysmal nocturnal dyspnea, lower limb edema , tachypalpitations,...etc ) 2. Clinical examination:
- Detecion of each patient body weight , height , calculation of BMI.
- General examination for detection of signs of Heart failure (raised JVP , lower limb edema, ..etc)
- Examination to respiratory system
- Auscultation of the heart for detection of valvular affection before echocardiography
Invesigations:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All patients echocardiographically diagnosed with significant valve lesions. Rheumatic Heart disease with significant but asymptomatic valvular Heart Disease especially (Mitral valve disease )(MS and MR) Gender: male & female
排除标准
- •Cases with increased level of BNP as in :
- •Renal impairment Advanced age and obesity Atrial fibrillation and acute coronary syndromes Prior lung diseases and acute illness
结局指标
主要结局
early detection of subclinical LV dysfunction.
时间窗: 1 year
early detection of subclinical LV dysfunction.
次要结局
未报告次要终点
研究者
Muhammad Khidr Ezzat thabet
Resident Doctor
Assiut University
研究点 (1)
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