Clinical Applicaitons of Non-Invasive Brain Stimulation for the Treatment of Chronic Pain
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Change in Average Daily Pain
研究概览
简要总结
The purpose of this study is to test whether non-invasive brain stimulation, such as Transcranial Magnetic Stimulation (TMS) may alleviate pain associated with various chronic pain conditions. We will test various methods of TMS to identify a treatment approach that may reduce the symptoms of chronic pain for the patient.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 or older
- •Patient with Chronic Low Back Pain
- •Meets minimum pain level criteria
- •Ability to perform the experimental Task and Procedures
排除标准
- •MRI contraindication if an MRI exam is required per protocol
- •TMS Contraindication
- •History of a psychological or psychiatric disorder that would interfere with study procedures, at the discretion of the researcher.
- •Neurologic illness that would interfere with brain integrity
- •Current medical condition or medication use that would interfere with study procedures or data integrity, at the discretion of the researcher.
- •Currently pregnant or planning to become pregnant.
- •On going legal action or disability claim.
研究组 & 干预措施
TMS Parameter Condition 1 first
Application of Transcranial Magnetic Stimulation
干预措施: Transcranial Magnetic Stimulation (Device)
TMS Parameter Condition 2 First
Application of Transcranial Magnetic Stimulation
干预措施: Transcranial Magnetic Stimulation (Device)
结局指标
主要结局
Change in Average Daily Pain
时间窗: Baseline Compared to each treatmeant series (at 4 weeks, 8 weeks, and 12 weeks)
Compared to baseline pain report as provided by Visual Analogue Scale (VAS)
Change in Worst Daily Pain
时间窗: Baseline Compared to each treatment series (at 4 weeks, 8 weeks, and 12 weeks)
As compared to baseline worst daily pain report provided on visual analogue scale (VAS)
次要结局
未报告次要终点
研究者
Sean Mackey
Chief, Division of Pain Medicine
Stanford University