ong-term StaphyloCoccus aureus decolonizAtion in patients on home parentRal nutRition: a randomized multicEnter tRial. - S. aureus decolonization in HPN patients/CARRIER-trial

Radboud Universitair Medisch Centrum0 个研究点目标入组 63 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

Trial is onging in other countries

•- Patient is fully able to understand the nature of the proposed intervention.
•- Patient is diagnosed with intestinal failure and on HPN and/or fluid replacement
•- Written informed consent by the patient before entering the trial.
•- Age * 18 years.
•- Estimated life expectancy * 1 year.
•- Patient colonized with S. aureus.

•- Cannot be expected to comply with the trial plan (substance abuse, mental condition).
•- Pregnant or breastfeeding women.
•- Continuous exposure to MRSA (e.g. pig farmer).
•- Allergy for chlorhexidine and betadine.
•- No options for oral and/or topical antibiotics due to allergies and/or resistance.
•- Active S. aureus infection.
•- Currently on treatment with antibiotics active against S. aureus.
•- Decolonization (including mupriocin) treatment in the previous two months.
•- The presence of an unremovable nasal foreign body.
•- AST and ALT levels more than five times the upper limit of normal or liver failure.

发起方