Microbiome Changes in Travelers to Tropical Destinations
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Type and number of intestinal microorganisms
研究概览
简要总结
The human gut contain a wide range of microorganisms creating the gut microbiome. The microbiome has great impact on metabolic and immunologic processes and responses. Travelers who travel to tropical destinations where the intestinal infection risk is high are prone to microbiome changes. During the current study the travelers will give feces specimen before and after the travel and their microbiome will be analyzed.
详细描述
Individual differences in the microorganisms variety are affected by external factors such as food, age, geographic location, medication consumption, host genetics and exposure to microorganisms in early stages of life. During the current study the geographic location affect will be tested by comparing the microorganism environment before and after traveling to tropical destinations.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Travelers who intended to travel to tropical areas
- •Good general health
排除标准
- •Medication consumption
- •Background diseases
结局指标
主要结局
Type and number of intestinal microorganisms
时间窗: 1 year
The participants microbiome will be analyzed before and after the travel. The type and number of microorganisms will be determined by microbiological measurements.
次要结局
未报告次要终点
研究者
Prof. Eli Schwartz MD, DTMH
Principal Investigator of geographic clinic
Sheba Medical Center