NCT02054390已完成不适用
Angiotensin Converting Enzyme Inhibitor Therapy and Periprocedural Myocardial Infarction in Patients With Metabolic Syndrome
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 459
- 试验地点
- 1
- 主要终点
- Periprocedural myocardial injury (MI)
研究概览
简要总结
Metabolic syndrome (MS) has been reported as a risk for cardiovascular events. The aim of the present cohort study is to investigate whether ACEi therapy reduces the rate of periprocedural myocardial injury (PPMI) after elective percutaneous coronary intervention (PCI) among patients with metabolic syndrome.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •metabolic syndrome
- •elective percutaneous coronary intervention with angiographically successful stent implantation
排除标准
- •acute coronary events
- •renal failure
- •needed the use of IV glycoprotein IIb/IIIa receptor inhibitors were excluded
- •left main coronary artery disease
- •chronic total occlusion
- •high levels of baseline CKMB or troponin
- •any contraindication of aspirin, clopidogrel or ACEi treatment
结局指标
主要结局
Periprocedural myocardial injury (MI)
时间窗: 24 hours after (percutaneous coroary intervention) PCI
Periprocedural MI was defined as cardiac Troponin I release \[5 times ULN\] 24 hours after percutaneous coronary intervention
次要结局
- Periprocedural myonecrosis(24 hours after PCI)
研究者
研究点 (1)
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