NCT05922826招募中不适用
Clinical Empirical Research of ARDS
Chinese PLA General Hospital1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2023年6月18日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Overall Survival
研究概览
简要总结
According to the ARDS Berlin definition, patients with severe concurrent invasive mechanical ventilation were selected, and clinical data and prognosis were collected. Samples such as blood and balf were collected for analysis based on changes in the condition.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who meet the Berlin definition of ARDS and require invasive mechanical ventilation. ARDS diagnostic criteria: according to the Berlin definition, Chest radiograph shows patchy shadows in the lungs; Respiratory failure cannot be completely caused by heart failure or excessive fluid infusion
- •ARDS onset ≤ 3 days when included in the study
- •Patient PaO2/FiO2 ≤ 200mmHg when included in the study
排除标准
- •Patients with intracranial hypertension, pleural fistula, pneumothorax, HIV, HBV, HCV
- •Age>85 years old or<18 years old
- •Pregnant patients
- •Severe hemodynamic instability (vasopressor increase>30% in the first 6 hours, or Norepinephrine>0.5 mg kg/min)
- •Patients unable to perform EIT ventilation and/or perfusion testing (unable to perform internal jugular vein catheterization, Hypernatremia, chest malformation, active implant device, unstable spinal injury or fracture, skin lesions opposite the EIT monitoring area)
- •Patients with abnormal esophageal anatomical structure and inability to indwelling gastric tubes
- •Disagreement for inclusion in this study
结局指标
主要结局
Overall Survival
时间窗: 28 days
次要结局
未报告次要终点
研究者
wang kaifei
Chinese PLA General Hospital
Chinese PLA General Hospital
研究点 (1)
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