Comparison of arterial to end tidal Carbon Dioxide gradient (Pa-ETCO2), in volume versus pressure controlled ventilation in patients undergoing robotic abdominal surgery in Trendelenberg Position (A randomised controlled study)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Arterial to end tidal carbon dioxide gradient measurement between pressure versus volume controlled ventilation
研究概览
简要总结
Minimally invasive surgeries are progressively replacing open surgeries. The ideal ventilatory strategy resulting in optimal lung dynamics is poorly understood.
We aim to evaluate the gradient of arterial carbon dioxide to the end tidal value between pressure and volume controlled ventilation during robotic surgery in the Trendelenberg position.
We also aimed to compare the arterial to alveolar oxygen gradient, peak airway pressures, dynamic compliance and p/F ratio between the two modes with an aim to identify the superior mode for these patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Scheduled to undergo robotic surgery in Trendelenberg position lasting for more than 2 hours.
排除标准
- •BMI > 35, ASA physical status III and above, respiratory disease and cardiac disease affecting ventilatory function.
结局指标
主要结局
Arterial to end tidal carbon dioxide gradient measurement between pressure versus volume controlled ventilation
时间窗: 1.Baseline in room air (T0) | 2. 10 minutes after pnuemoperitoneum (T1) | 3. 2 h after surgery (T2) | 4. 2 hrly during surgery (T3, T4) | 5. 10 mins after deflation of pnuemoperitoneum (Te)
次要结局
- 1. Alveolar to arterial gradient (A-a)DO2(2.Peak airway pressure)