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临床试验/NCT03519789
NCT03519789已完成不适用

Cognitive and Emotional Factors in Visual Exploration Among Patients With Post-Traumatic Stress Disorder

University Hospital, Lille2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2014年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
80
试验地点
2
主要终点
Response time before the detection of neutral and emotional stimuli.

研究概览

简要总结

Post-traumatic stress disorder (PTSD) is characterized by hypervigilance. In particular, previous works suggest that patients tend to scan constantly the environment for possible threats. The present project aims at investigating such attentional bias in patients with PTSD using the change blindness paradigm that offers the interesting possibility of studying sensitivity to sudden changes using ecological stimuli. More precisely, the investigators will investigate whether patients are more sensitive than matched controls to sudden changes in the visual environment and whether this hypersensitivity is specific or even stronger when visual information has an emotional content. The attentional bias will be measured using motor responses (accuracy and speed to indicate the occurrence of a change by pressing a button) as well as eye movements.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • a diagnosis of PTSD based on the standard DSM-IV criteria,
  • normal or corrected vision.
  • clinically stable at the testing time

排除标准

  • history of neurological illness or trauma that occurred in the previous six months, - pregnant and nursing women,
  • drugs use in the last 24 hours,
  • an acute ocular disorder.
  • Participants will not be under tutorship, curatorship or deprived of liberty.

研究组 & 干预措施

Controls

30 healthy controls without any psychiatric or neurological diagnosis

Post-Traumatic Stress Disorders (PTSD)

30 patients with PTSD (diagnosis based on the standard DSM criteria)

结局指标

主要结局

Response time before the detection of neutral and emotional stimuli.

时间窗: Baseline: one session

The explicit response of the participants will be measured with the response time before the detection of neutral and emotional stimuli.

次要结局

  • Number of correct detections compared with the missed detections and false alarms.(Baseline: one session)
  • Total duration until the participant first fixed on a ROI.(Baseline: one session)

研究者

发起方
University Hospital, Lille
申办方类型
Other
责任方
Sponsor

研究点 (2)

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