Histologic Response to UVA and UVB Exposure During the Use of Sunscreen With Anti-inflammatory and Anti-oxidant Properties - A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2
- 试验地点
- 1
- 主要终点
- H&E Staining
研究概览
简要总结
Anti-inflammatory and anti-oxidant agents have become the important ingredients in sunscreen. However, there is no histologic study about the effects of anti-inflammatory and anti-oxidative properties of sunscreen to prevent premature aging from UVA and UVB.
详细描述
Premature aging can be prevented by using sunscreen. Currently, anti-inflammatory and anti-oxidant agents have become the important ingredients in sunscreen. However, there is no histologic study about the effects of anti-inflammatory and anti-oxidative properties of sunscreen to prevent premature aging from UVA and UVB.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 35 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •subjects aged 35-65 years who were scheduled for abdominoplasty
- •the excised area should be larger than 18x10 cm2
- •no skin diseases or lesions on the excised area
- •no topical treatment on excised area more than 1 month prior to this study
排除标准
- •pregnancy
- •lactation
- •have tattoo or striae distensae on abdomen
研究组 & 干预措施
Sunscreen
Apply sunscreen before and after UVA and UVB irradiation
干预措施: Sunscreen (Other)
结局指标
主要结局
H&E Staining
时间窗: 2 Months
Review difference in H\&E staining in tissue biopsy before and after UVA / UVB irradiation
次要结局
- Tyrosinase Staining(2 Months)