Evaluation of Microbial Composition in Human Milk From Healthy Women in the Turkish Population: an Observational Cross-sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Microbial abundance and diversity
研究概览
简要总结
Breast milk is an optimal source of nutrients for newborns as well as a potential source of bacteria for the intestinal microbiota. However, there are limited number of studies evaluating the relationship between maternal nutrition, breast milk and neonatal intestinal microbiota.
详细描述
The study was conducted on a total of 20 healthy women following at Obstetrics and Gynecology Department of Gülhane Education and Research Hospital in Ankara Health Sciences University. Sociodemographic characteristics, anthropometric measurements, breastfeeding characteristics were evaluated in the third trimester of the women who underwent routine prenatal care. Breast milk samples were obtained at 16.day postpartum during lactation.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 31 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Singleton pregnancy
- •Age 19-35 years
- •At weeks of 30-36 gestation
- •No history of acute or chronic diseases
- •Term delivery
排除标准
- •Alcohol use
- •Gestational diabetes
- •Type 1 and 2 diabetes
- •Preeclampsia
- •Polycystic ovary
- •Thyroid and parathyroid disease
- •Metabolic bone or kidney disease
- •Abnormal liver function
- •Multiple pregnancy
- •Premature and postmature labor
- •Having chemotherapy
- •Taking drugs such as antibiotics and probiotics
结局指标
主要结局
Microbial abundance and diversity
时间窗: at 16 day postpartum
The microbial composition of the breast milk samples was determined by 16S rRNA (ribosomal ribonucleic acid) gene sequencing analysis.
次要结局
未报告次要终点
研究者
F. Gülhan Samur
Prof. Dr.
Hacettepe University