Benefits of Pulmonary Rehabilitation in Patients With Severe Lymphangioleiomyomatosis (LAM) - a Retrospective Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- Change from baseline 6 Minute walk distance at week 4
研究概览
简要总结
Data from patients with the orphan disease of lymphangioleiomyomatosis (LAM) which performed a pulmonary Rehabilitation program will be analyzed retrospectively. Data will be taken from the internal data base of the reference Center (Schoen Klinik Berchtesgadener Land, Schoenau, Germany) where These data were collected during clinical routine. Data will be included from the year 2000 until now. A retrospectively matched COPD cohort will be included for comparison.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •confirmed diagnosis of Lymphangioleiomyomatosis
- •performed a pulmonary Rehabilitation program at the reference center
排除标准
- •missing data
- •repeated stay for pulmonary Rehabilitation at the reference center
结局指标
主要结局
Change from baseline 6 Minute walk distance at week 4
时间窗: baseline and week 4
the walked distance in meter will be the Primary outcome of the 6 Minute walk test
Change from baseline Quality of life at week 4
时间窗: baseline and week 4
the physical and mental health component summary score from the Short Form 36 Health Questionnaire will be recorded. Score range from 0 to 100 with lower scores indicating worse impairment
次要结局
- Change from baseline lung function at week 4(baseline and week 4)
研究者
Klaus Kenn
Prof. Dr.
Schön Klinik Berchtesgadener Land