Sepsis in ICU: Causes and Outcomes in Diabetics and Non Diabetics in Assiut University Hospital
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 85
- 主要终点
- Detect the most common organism causing sepsis in ICU
研究概览
简要总结
Identify prevalence of sepsis in ICU of Assiut university hospital 2.Clarify different causes of sepsis in patients admitted to ICU . 3.Compare causes and outcomes of sepsis between diabetics versus non diabetics .
4.Screening for the co1.mmonest organism causing sepsis in critically ill patients .
详细描述
Sepsis, is defined as an infection with organ dysfunction, There is wide variation in sepsis rates, causative microorganisms, and outcome in ICU patients around the world.
Many conservative estimates considered sepsis as a leading cause of mortality and critical illness worldwide .
sepsis epidemiology studies worldwide revealed a highly variable incidence of 13-300 per 100,000 inhabitants per year for severe sepsis and 11 per 100,000 inhabitants per year for septic shock .
Factors such as advancing age, immunosuppression and multidrug-resistant infection play a role in increasing incidence of sepsis during recent decades .
Patients who survive sepsis often have long-term physical, psychological, and cognitive disabilities with significant health and social implications.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •according to sofa criteria Suspected /documented infection+sofa score >_2 or +ve Q sofa defined as 2or more 1_ hypotesion SBP<90.2_altered mental status GCS<13 3_
排除标准
- •tachypnea>22 or septic shock criteria
- •previous history of pulmonary problem Previous history of cardiac disease Previous history of autoimmune disease
结局指标
主要结局
Detect the most common organism causing sepsis in ICU
时间窗: 20 days
Applying culture and sensitivity test for patients developed sepsis on admission and follow up will direct us for appropriate treatment for all patients
次要结局
- Incidence of sepsis in diabetics versus non diabetics in ICU.(15 days)
研究者
Mai Ahmed fathi mansour
Specialist
Assiut University