NCT06441279已完成不适用
Hyaluronic Acid Versus Platelet Lysate in The Treatment of Temporomandibular Joint Anterior Disc Displacement With Reduction: A Randomized Clinical Trial
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Maximum inter-incisal opening
研究概览
简要总结
comparing the clinical efficacy of intra-articular injection of platelet lysate (PL), versus Hyaluronic Acid after arthrocentesis in the management of patients with anterior disc displacement with reduction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients that will be diagnosed with anterior disc displacement with reduction (ADDWR) both clinically and through magnetic resonance imaging scan (MRI).
- •Patients who will not respond to a previous conservative therapy.
- •Patients with pain in temporomandibular joints.
- •Patients with normal or limitation in mouth opening.
- •Patients with clicking sound.
排除标准
- •Patients with previous invasive TMJ surgical procedures.
- •Patients with inflammatory or connective tissue diseases.
- •Patients with neurologic disorders.
- •Patients with history of bony or fibrous adhesion.
- •Patients having gross mechanical restrictions and condylar fractures.
- •Patients with psychological problems.
- •Patients receiving anti-coagulation treatment, non-steroidal anti-inflammatory drugs within 48 hours pre-operatively, corticosteroid injection at the treatment site within one month or systemic use of corticosteroids within 2 weeks.
结局指标
主要结局
Maximum inter-incisal opening
时间窗: 6 months
Maximum inter-incisal opening will be measured by Vernier caliper and this will be recorded by photographs.
次要结局
未报告次要终点
研究者
研究点 (2)
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