Effects of Two Physical Exercise Protocols on Cognition and Physical Performances in Oldest Old: a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 69
- 试验地点
- 2
- 主要终点
- Changes from baseline in balance after 16 weeks of training and 6 weeks of detraining
研究概览
简要总结
The purpose of this study is to compare the effects of different trainings on cognition and physical performances in elderly over 80 years.
详细描述
Purpose: To compare the effects of 16-week multicomponent and resistance trainings on cognition and physical performances related to falls in oldest old people living in community; to analyze the same variables after 6-week detraining. Method: We conducted a randomized controlled trial with 69 community elderly over 80 years, sedentary and without cognitive disorder. Participants were allocated to control, multicomponent training or resistance training group. The multicomponent group performed a protocol involving warm-up, aerobic, strength, balance and cool-down exercises. The resistance group underwent to strength exercises using six machines: leg press, chest press, calf, back extension, abdominal and rowing. The control group did not perform any intervention. The trainings had progressive intensity, lasted 16 weeks and included three 1-hour sessions per week. The participants were evaluated at baseline, at the end of 16-week training and at 6-week detraining. The assessment consisted of anamnesis, depression (Geriatric Depression Scale), cognition (Montreal cognitive assessment), dual task walking (associated to cognitive and motor tasks), balance (unipedal and tandem tests), strength of lower limbs (sit-to-stand test) and history of falls. For statistical analysis by intention to treat, we adopted a significance level of α=0.05.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 80 Years 至 95 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age between 80 and 95 years old
- •live in community
- •sedentary lifestyle
- •ability to walk without help from another person with/without aid walking
排除标准
- •any cardiovascular or infectious comorbidity described in the absolute contraindications of the Physical Activity Readiness Medical Examination
- •Relative contraindications of cognitive, neurological and/or musculoskeletal comorbidities which make participation in protocols impossible
- •Score in mini-state examination mental below the cutoff score designated by education level.
结局指标
主要结局
Changes from baseline in balance after 16 weeks of training and 6 weeks of detraining
时间窗: Assessed at baseline, after 16 weeks of training and 6 weeks of detraining
Balance was assessed by unipedal test and tandem test.
Changes from baseline in dual task walking after 16 weeks of training and 6 weeks of detraining
时间窗: Assessed at baseline, after 16 weeks of training and 6 weeks of detraining
Dual task was assessed by Timed Up and Go test with a cognitive task (speak day of week in reverse order) and motor task (carry a cup of water).
Changes from baseline in lower limbs strength after 16 weeks of training and 6 weeks of detraining
时间窗: Assessed at baseline, after 16 weeks of training and 6 weeks of detraining
Lower limbs strength was assessed by 5 times sit-to-stand test.
Changes from baseline in cognition after 16 weeks of training and 6 weeks of detraining
时间窗: Assessed at baseline, after 16 weeks of training and 6 weeks of detraining.
Cognition was evaluated by Montreal Cognitive Assessment.
次要结局
- Changes from baseline in number of falls after 16 weeks of training and 6 weeks of detraining(Assessed at baseline, during 16 weeks of training and 6 weeks of detraining.)
- Changes from baseline in depression after 16 weeks of training and 6 weeks of detraining(Assessed at baseline, during 16 weeks of training and 6 weeks of detraining.)
研究者
Juliana Hotta Ansai
Principal investigator
Universidade Federal de Sao Carlos