Analysis of Operative Outcomes Following Endoscopic Resection of Pituitary Adenomas
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 2
- 主要终点
- Diabetes insipidus
研究概览
简要总结
The goal of this prospective study is to learn about the operative outcomes in patients with pituitary adenoma who receive endoscopic resection.
The main question it aims to answer is:
• What are the outcomes of patient following endoscopic resection? including visual, hormonal, survival, and functional outcomes.
Participants' data including clinical history, laboratory data, radiographic images, intraoperative videos will be evaluated and analyzed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patient
- •Pathological diagnosis of pituitary adenoma
- •Underwent endoscopic endonasal resection
排除标准
- •Age < 18 or > 80 years
- •Non-pituitary adenoma pathologies
- •Underwent non-endoscopic surgery
研究组 & 干预措施
Endoscopic endonasal surgery
Patients who received endoscopic endonasal resection of pituitary adenomas
干预措施: Endoscopic endonasal surgery (Procedure)
结局指标
主要结局
Diabetes insipidus
时间窗: 6 months
Postoperatively, the patient's urine output and urine specific gravity will be measured to determine if the patient had diabetes insipidus. If the patient had diabetes insipidus, the duration of the diabetes insipidus will be recorded.
Cortisol level
时间窗: 6 months
Postoperative serum cortisol level will be measured and compared to preoperative levels.
Visual field
时间窗: 6 months
The postoperative visual field will be assessed with standard visual perimetry and compared with preoperative measurements.
Thyroid hormone level
时间窗: 6 months
Postoperative serum TSH and free T4 level will be measured and compared to preoperative levels.
IGF-1 level
时间窗: 6 months
Postoperative serum IGF-1 level will be measured and compared to preoperative levels.
Prolactin level
时间窗: 6 months
Postoperative serum prolactin level will be measured and compared to preoperative levels.
次要结局
未报告次要终点