Patterns of Renal & Urinary Involvement in Patients With Inflammatory Bowel Diseases Who Attended to Assiut University Hospitals
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 主要终点
- Patterns of renal and urinary involvement in IBD patients
研究概览
简要总结
Detection and classification of different renal and urinary affection in patients with IBD that attended to Assist University Hospitals
详细描述
Background (Research Question, Available Data from the literature, Current strategy for dealing with the problem, Rationale of the research that paves the way to the aim(s) of the work). (200-250 words max.) Inflammatory bowel disease is an idiopathic disease cause sever inflammation of GIT , presentes in ulcerative colitis or Crohn's disease occur in 6%-47%
IBD is profoundly associated with extra intestinal manifestions , Especially renal and urinary involvement occurs in 4% - 23% of patients with IBD.
Patterns of renal complications include nephrolithiasis, glomerulonephritis, amyloidosis, AKl, CKD, tubulointerstitial nephritis, asymptomatic proteinuria and hematuria; each type has specific mechanism
Nephrolithiasis is 10-100 times greater in IBD patients than general population.most common stones are calcium, oxalate and urate; Stones occur due to loss of electrolytes "Mg,k" due to diarrhea which lead to crystallization.
Glomerulonephritis pattern in IBD , is associated with IgA nephropathy, IgM nephropathy, membranous and focal segmental glomerulonephritis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •100 patients suffering of IBD who attended to AUH either with Crohn's or ulcerative colitis with different presentation
排除标准
- •Patients with other known cause of kidney or urinary affection as DM,HTN,APCKD, lupus nephritis,UTI.....
结局指标
主要结局
Patterns of renal and urinary involvement in IBD patients
时间窗: 2 years
Is renal and urinary system affect on IBD patients ?
次要结局
未报告次要终点
研究者
Rania Essam Mohamed
Assistant Lecturer
Assiut University