Microvascular flow and microvascular blood volume measurements in human skeletal muscle using contrast enhanced ultrasound (CEUS). - CEUS reproducibility study.

niversiteit Maastricht0 个研究点目标入组 8 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•1. Age 18-55 years
•2. BMI < 25 kg/m2 *;* = most likely to have intact capillary recruitment in skeletal muscle (a parameter studied in this research protocol).

•1. Cardiovascular disease (stroke, coronary artery disease, peripheral vascular disease, heart failure, cardiac shunts, heart valve replacement, pulmonary hypertension).
•2. Pulmonary disease.
•3. Diabetes mellitus (FPG > 7.8 mmol/L).
•4. Smoking.
•5. Hypertension (>140/90 mmHg).
•6. Alcohol use > 4 U/day.
•7. Use of medication (antihypertensive medication, statins, corticosteroids, NSAIDs, ciclosporin A, rifampicin).
•8. Pregnancy or lactation.
•9. Insufficient knowledge of the Dutch language.
•10. Known allergic reaction to ultrasound contrast-agent.
•11. Known cardiac dysrhythmias (e.g. atrial fibrillation, long QT-syndrome) or a family history of cardiac dysrhythmias or sudden cardiac death.

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