Impact of Belt Position on the Results of PEEP Titration by Electrical Impedance Tomography During Acute Respiratory Distress Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 主要终点
- Impact of the position of the electrode belt on the results of PEEP titration by EIT.
研究概览
简要总结
ARDS is a frequent reason for hospitalization in intensive care. In order to improve its management, doctors seek to limit the mechanical ventilation-induced injuries (VILI) that can occur. PEEP is a parameter that plays a role in the appearance of VILI, and its adjustment can be optimized by EIT. The EIT is a non-invasive, non-irradiating, real-time monitoring device, today widely used for the optimization of ventilation in patients intubated for ARDS. The positioning of the EIT belt at different chest heights could influence the result of the PEEP titration.
详细描述
The aim of this study is to test the hypothesis that the position (2nd intercostal space or 5th intercostal space) of the EIT (Electrical Impedance Tomography) belt significantly influences the result of PEEP (Positive Expiratory Pressure) titration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Occurrence of moderate to severe ARDS (PaO2/FiO2 ratio ≤ 200 mmHg) within 72 hours following intubation
- •Criteria for moderate to severe ARDS for less than 72 hours
- •Passive ventilation in controlled assisted ventilation (no spontaneous ventilation)
- •Consent of next of kin
排除标准
- •Age < 18 years
- •Pneumothorax
- •Pacemaker or implantable defibrillator
- •Chest trauma in the last 3 months
- •Skin peeling (Burned, Lyell)
- •Intracranial hypertension
- •Uncontrolled shock (noradrenaline >5 mg/h)
- •Pregnant woman
- •Adult patient protected within the meaning of the law
- •Lack of social security
研究组 & 干预措施
PEEP titrations
干预措施: EIT (Device)
结局指标
主要结局
Impact of the position of the electrode belt on the results of PEEP titration by EIT.
时间窗: Day 0
Optimal PEEP determined by PEEP titration using the crossing point method.
次要结局
- Discrepancy between compliance measured according to impedance and compliance measured according to exhaled volume(Day 0)
- Factors associated with a discordance between PEPEIT and PEPCRS(Day 0)
- Impact of the existence of intra-tidal recruitment on the discordance between PEPEIT and PEPCRS(Day 0)