Concentrated Growth Factor Versus Platelets-rich Fibrin in Revascularization of Immature Necrotic Mandibular First Permanent Molar.
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- root growth
研究概览
简要总结
in this study investigators do revascularization technique to promote root growth of immature mandibular first permanent molar by using CGF and PRF from blood sample of patients
详细描述
children 6-8 yrs were selected for this study because the roots of mandibular first permanent molar is not completed. then access cavity is opened, irrigation protocol is applied, intracanal medication is applied and the cavity is sealed with temporary filling. after three weeks blood sample is obtained from patients to get CGF and PRF membranes. temporary filling is removed . intracanal medication is removed, over instrumentation is done to get some intracanal blood the wait tell blood clot is formed then CGF or PRF is applied on the clot the bio dentine is applied and cavity is sealed with composite restoration
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 6 Years 至 8 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children with immature necrotic lower fitrst permanent molar.
- •No history of repeated pathosis or cellulitis.
- •Patients accept the treatment modality.
- •Patient-free from systemic, allergic or genetic problems.
排除标准
- •Tooth mobility.
- •Teeth with non-restorable crowns.
- •Children with facial cellulitis
- •Children with draining fistula
- •Children with a history of recurrent preapical pathosis
研究组 & 干预措施
CGF and biodentine arm
(control group) Which CGF and bio-dentine are applied to the immature pulp of the first permanent molar
干预措施: Revascularization/Conservative management (Biological)
PRF and biodentine arm
PRF and bio-dentine are applied on immature pulp of first permanent molar
干预措施: Revascularization/Conservative management (Biological)
结局指标
主要结局
root growth
时间窗: 18 months
change root length
次要结局
未报告次要终点
研究者
Bothaina Ahmed
Assistant lecturer in Pediatric and Community Department, South Valley University Faculty of Dentistry
Minia University