NCT01553435Unknown不适用
Effect of N-methyl D-aspartate (NMDA) Receptor Antagonist Dextromethorphan on Opiods Analgesia and Tolerance in Pediatric Intensive Care Unit Patients
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Effect of N-methyl D-aspartate (NMDA) receptor antagonist Dextromethorphan on Opiods analgesia and tolerance in Pediatric Intensive Care Unit Patients
研究概览
简要总结
Effect of N-methyl D-aspartate (NMDA) receptor antagonist Dextromethorphan on Opiods analgesia and tolerance in Pediatric Intensive Care Unit Patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 2 Years 至 14 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Patients under 2 years of age
- •Patients with anticipated PICU length of stay less than 3 days.
- •Patients shall be excluded if Morphine or Fentanyl infusions not continued for the minimum duration of 72 hours after enrollment
- •Patients develops hemodynamic instability
- •Patients with Hepatic failure
- •Withdrawal request by parent(s)/guardian/family
研究组 & 干预措施
Dextromethorphan, opioid analgisia, efficacy
Placebo Comparator
干预措施: Dextromethorphan (Drug)
Placebo,opioid analgesia, efficacy
Placebo Comparator
干预措施: Placebo (Drug)
结局指标
主要结局
Effect of N-methyl D-aspartate (NMDA) receptor antagonist Dextromethorphan on Opiods analgesia and tolerance in Pediatric Intensive Care Unit Patients
时间窗: Two years
Control of pain
次要结局
- Effect of N-methyl D-aspartate (NMDA) receptor antagonist Dextromethorphan on Opiods analgesia and tolerance in Pediatric Intensive Care Unit Patients(Two years)
研究者
Mohammed Naeem
Consultant Pediatric Intensivist
King Abdullah International Medical Research Center
研究点 (1)
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