Photodynamic Therapy With Polyhematoporphyrin for Malignant Biliary Obstruction - a Retrospective Analysis.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 88
- 主要终点
- Safety of photodynamic therapy
研究概览
简要总结
Photodynamic therapy (PDT) is a palliative treatment for malignant biliary obstruction. The aim of this study is to assess the feasibility and safety of this technique in the context of a nationwide retrospective analysis.
详细描述
INTRODUCTION
Malignant biliary obstruction is a life threatening condition in patients suffering from primary or secondary bile duct malignancies. Palliative therapies aim to prevent complications associated with the obstruction. Photodynamic therapy (PDT) aims to reduce the local tumor mass by inducing tumor necrosis after light activation of a photosensitizer during endoscopic retrograde cholangiography (ERC).
STUDY AIMS
The aim of the present study is to evaluate the feasibility and safety of PDT with polyhematoporphyrin, the photosensitizer most commonly used for PDT in Austria, in the context of a nationwide analysis.
METHODS
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Undergone photodynamic therapy as a treatment for malignant biliary obstruction.
排除标准
- 未提供
结局指标
主要结局
Safety of photodynamic therapy
时间窗: 30 days
Treatment emergent adverse events
次要结局
- Efficacy of photodynamic therapy(From date of first photodynamic therapy until date of death from any cause, assessed up to 100 months)
研究者
Werner Dolak, MD
Assistant doctor
Medical University of Vienna