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临床试验/NCT07596056
NCT07596056尚未招募不适用

IMPULSION: Long-Term Engagement and Motivation Through Innovative Strategies in Adapted Physical Activity

Centre Hospitalier Universitaire de Nice1 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2026年9月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
600
试验地点
1

研究概览

简要总结

Aging is associated with progressive declines in physical, functional, and psychosocial capacities, leading to reduced autonomy, increased risk of falls, chronic diseases, and decreased quality of life. Physical inactivity is a major aggravating factor, despite strong evidence that regular physical activity helps prevent age-related decline.

Adapted Physical Activity (APA) has demonstrated beneficial effects on physical function, mental health, pain, and healthcare utilization. However, long-term adherence to APA programs among older adults remains low, with fewer than 20% meeting World Health Organization recommendations. Therefore, innovative strategies are needed to improve sustained engagement in physical activity.

This multicenter, randomized, single-blind interventional study aims to compare the effectiveness of different APA strategies on long-term engagement in physical activity among adults aged 60 years and older.

A total of 600 participants will be randomized into four groups combining two key factors: (1) autonomy-based vs. non-autonomy-based approaches, and (2) classical APA vs. TEMPA-based APA programs. Each intervention consists of a 12-week program including 24 supervised sessions, with some groups incorporating a progressive transition toward autonomous practice.

The primary outcome is long-term physical activity engagement assessed using the QAPPA questionnaire at baseline, 6 months, and 12 months.

Secondary outcomes include:

Objective and self-reported physical activity levels (questionnaires and wearable devices) Functional capacities (muscle strength, endurance, gait speed, balance, cardiorespiratory fitness) Motivational and perceptual factors (e.g., enjoyment, fatigue, perceived effort, motivation) Quality of life (EQ-5D-5L) Biological markers (inflammatory, metabolic, metabolomic, and epigenetic profiles) to identify predictors of adherence and physiological response Cost-effectiveness and cost-utility analyses (incremental cost-effectiveness ratio)

Statistical analyses will be conducted using mixed linear models for repeated measures to evaluate time, group, and interaction effects. Additional analyses will include descriptive statistics, group comparisons, longitudinal trends, and economic evaluations.

This study aims to identify effective and sustainable APA strategies to improve long-term physical activity engagement and inform public health policies for older adults.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 60 or older
  • Affiliation with, or beneficiary of, a social security system
  • No objection to the study

排除标准

  • Neurocognitive disorder preventing the provision of informed consent (MOCA <18)
  • Individuals under legal protection
  • Individuals deprived of liberty
  • Presence of a physical or cognitive condition preventing participation in the adapted physical activity protocol over 3 months:
  • Neurocognitive disorder (MOCA <18)
  • Neurodegenerative disease with severe symptoms preventing participation in the protocol
  • Neuromuscular disease with severe symptoms preventing participation in the protocol
  • Severe sensory impairments (blindness or profound deafness)
  • Amputation of one or more limbs
  • Non-independent mobility

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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