Dexamethasone Versus Dexmedetomidine as Adjuvant to Bupivacaine in Sphenopalatine Ganglion Block as Post-operative Analgesia in Rhinoplasty Surgeries
试验速览
- 阶段
- 1 期
- 状态
- Enrolling By Invitation
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- The time to the first request of analgesia
研究概览
简要总结
This study will test the effect of adding dexamethasone versus dexmedetomidine as adjuvants to bupivacaine in sphenopalatine ganglion block used for pain after rhinoplasty
详细描述
Preoperative settings:
Preoperative evaluation of full medical history will be taken, examination will be done, and routine preoperative investigations will be done to all patients including complete blood picture and coagulation profile.
The patient will be fasting for at least 8 hours preoperatively
Intraoperative settings:
General anesthesia technique:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-65 years.
- •Sex: of either sex.
- •American Society of Anaesthesiologists (ASA) Physical Status Class I and II.
- •Scheduled for rhinoplasty surgeries under general anaesthesia.
排除标准
- •Declining to give written informed consent.
- •History of allergy to the medications used in the study.
- •Contraindications to regional anesthesia (including patient refusal, coagulopathy and local infection).
- •Psychiatric disorder.
研究组 & 干预措施
Group BD
Group BD: will receive bupivacaine 0.25% (3ml) + dexamethasone (4mg), total volume 5ml by adding normal saline
干预措施: Dexamethasone (Drug)
Group B
Group B (control group): will receive bupivacaine 0.25% (3ml) + normal saline, total volume (5 ml).
干预措施: Bubpivacaine (Drug)
Group BDX
Group BDX: will receive bupivacaine 0.25% (3ml) + dexmedetomidine (1 mic/kg), total volume 5ml by adding normal saline.
干预措施: Dexamedomedine (Drug)
结局指标
主要结局
The time to the first request of analgesia
时间窗: 9 months
The time interval between the onset of the local infiltration done at the end of the operation and the first request to postoperative analgesia
次要结局
未报告次要终点