The Effectiveness of Advanced Decision Support Tool (OPT-IVF) for IVF Treatment
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- total cumulative dosage of Gonadotropins
研究概览
简要总结
This prospective study is subject to approval of institutional medical research ethics committee. Patient undergoing second cycle IVF will be enrolled into the intervention group. Intervention involved using a clinical decision support tool, Opt-IVF to guide gonadotrophins dosing and trigger dates for a personalized controlled ovarian stimulation cycle based on the distribution of follicle sizes on day 1 and day 5, and hormone dosages given on day 1 to 4.
Patients will undergo transvaginal ultrasound exam on day 1 and day 5 of the cycle to determine the number and size of follicles present. The data is used in the Opt-IVF decision support tool to suggest Gonadotropin dosage for D5 and beyond and to recommend the antagonist start day and trigger day.
Clinical investigators will not override the Opt-IVF recommended dosage in any patients.
详细描述
The total dosage of gonadotrophin, number of good quality oocytes and blastocyst will be analyzed from each arm.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Patient undergoing 2nd cycle of IVF
排除标准
- •Polycystic ovarian syndrome patient
结局指标
主要结局
total cumulative dosage of Gonadotropins
时间窗: for 1 year duration
number of total dosage that utilize during one cycle of IVF treatment
Total number of matured oocytes
时间窗: for 1 year duration
number of matured oocytes following the stimulation protocol
total number of good quality blastocyst
时间窗: for 1 year duration
total blastocyst achieved after each sti,ulation protocol
次要结局
未报告次要终点
研究者
Azrai Abu
Associate Prof
National University of Malaysia