NCT06202469已完成不适用
The Effects of 8-week Creatine Supplementation With and Without Ubiquinol on Sperm Quality Biomarkers in Normospermic and Oligospermic Men
University of Novi Sad, Faculty of Sport and Physical Education2 个研究点 分布在 1 个国家目标入组 18 人开始时间: 2023年12月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 18
- 试验地点
- 2
- 主要终点
- Sperm concentration
研究概览
简要总结
This randomized controlled double-blind parallel-group interventional trial explores the impact of 8-week creatine supplementation, with or without ubiquinol, on sperm quality biomarkers in normospermic and oligospermic men. It aims to determine potential enhancements in sperm health to provide insights into male fertility and reproductive health improvement strategies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Age 18 - 35 years
- •Sperm quality test available (at least half will have low sperm quality)
- •Informed consent
- •Healthy BMI (18.5 - 24.9 kg/m2)
排除标准
- •Major chronic disease and acute injuries
- •History of dietary supplement use during the past 28 days
- •No consent to randomization
- •Participation in other studies
结局指标
主要结局
Sperm concentration
时间窗: Change from baseline sperm concentration at 8 weeks
Number of sperm per milliliter of semen
次要结局
- Total antioxidant capacity(Change from baseline total antioxidant capacity at 8 weeks)
- Creatine kinase(Change from baseline creatine kinase at 8 weeks)
- The World Health Organisation-Five Well-Being Index (WHO-5)(Change from baseline WHO-5 at 8 weeks)
- Creatine(Change from baseline creatine at 8 weeks)
研究者
Sergej Ostojic
Professor
University of Novi Sad, Faculty of Sport and Physical Education
研究点 (2)
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