ACTRN12610000397011招募中2 期
The effect of low dose colchicine(1mg/dy) administered to patients with stable coronary artery disease compared with no treatment on brachial artery flow mediated dilation and blood inflammatory markers.
Pfizer Cardiovascular Lipid Research Grant0 个研究点目标入组 40 人开始时间: 2010年5月18日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 80 Years（—）
- 性别
- All
入选标准
- •18 to 80 years old.
- •Male and female.
- •History of proven coronary artery disease by coronary agnigraphy. (>50% stenosis of epicardial coronary artery or requirement for percutaneous coronary intervention)
- •Stable for >1 month
- •No significant co-morbidity that will affect followup.
- •No contraindication to colchicine use.
排除标准
- •Any patient who is not deemed to have stable coronary artery disease.
- •Mild coronary artery disease.
- •Advanced heart failure (New York Heart Association grade 3 or 4).
- •Renal failure with creatnine clearance(<30ml/min/1.73m2).
- •Known malignancy.
- •Inflammatory bowel disease.
- •Requirement for cyclosporine or other drugs that may interact with colchicine.
- •Known sensitivity to colchicine.
- •Pregnancy or contemplated pregnancy during the study period.
研究者
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