NCT00291239Unknown4 期
Phase 4 Study on the Effect of Partial Sleep Deprivation on Cognition and the IL-6-gp130-System in Individuals With Major Depression
Zentrum für Integrative Psychiatrie2 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2006年2月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- cognition
研究概览
简要总结
40 patients with the diagnosis of major depression are included. There are two interventions: partial sleep deprivation (PSD) and normal night sleep (CTRL). Patients are randomly assigned to PSD-(2 undisturbed nights)-CTRL or CTRL-(2 undisturbed nights)-PSD. Cytokine-status, neuropsychological and psychopathometric status are assessed pre and post each interventional and control condition.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Major depression
- •Informed consent
排除标准
- •Known epilepsy or previous unexplained loss of consciousness after sleep deprivation
- •Bipolar disorder
- •Acute or chronic inflammatory diseases
- •Psychosis
- •Suicidal tendency
- •Pregnancy or nursing
结局指标
主要结局
cognition
cytokine concentration
次要结局
- clinical improvement
研究者
研究点 (2)
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