ACTRN12621001346864招募中未知
Head COOLing in iscHaemic stroke patients undergoing EndovAscular thrombectomy: a feasibility stuDy (COOLHEAD-2).
Professor P. Alan Barber0 个研究点目标入组 40 人开始时间: 2021年10月7日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Patients with anterior circulation large vessel occlusion stroke (internal carotid artery, M1 or proximal M2 segments of the middle cerebral artery) where endovascular clot retrieval is planned.
排除标准
- •- Pre-stroke modified Rankin Scale score >2
- •- BP >=185/110 mmHg not responsive to guideline-directed intravenous antihypertensive
- •- Admission core body temperature <35°C
- •- Known contraindications to hypothermia, including haematological dyscrasias that affect
- •thrombosis (cryoglobulinemia, sickle cell disease, serum cold agglutinins), or vasospastic
- •disorders such as Raynaud's or thrombo-angiitis obliterans
- •- Skin lesions not allowing secure application of the cooling cap
- •- Unable to participate in follow-up at 3 months (e.g., travelling overseas)
- •- Terminal illness with expected survival <1 year
研究者
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