NCT06408922已完成不适用
Comparison of the Effects of Single Versus Triple Injections of Platelet-Rich Plasma in Patients With Knee Osteoarthritis
Izmir Democracy University1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2023年4月15日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- The Western Ontario and MacMaster Universities (WOMAC) Osteoarthritis Index
研究概览
简要总结
80 patients diagnosed with knee osteoarthritis were randomized into two groups: patients in Group 1 received a single intraarticular injection of PRP whereas those in group 2 were administered three intraarticular injections of PRP within an interval of 2 weeks between each application. Patients were evaluated before the treatment and at the 6 month after the treatment with a Visual Analog Scale (VAS) and The Western Ontario and MacMaster Universities (WOMAC) Osteoarthritis Index.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 35 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ages of 35 and 80
- •Kellgren-Lawrence grade of 2, 3, or 4
排除标准
- •rheumatic diseases, coagulopathies, severe cardiovascular diseases, local infections, malignancies, immunodeficiency, schizophrenia, mental retardation, anticoagulant therapy, a hemoglobin concentration of 11 g/dL and platelets of 150,000/L, a history of severe trauma, or a history of hyaluronic acid or corticosteroid injection within the previous 6 months
研究组 & 干预措施
Single prp injection
Active Comparator
single intraarticular prp injection
干预措施: prp injection (Other)
triple prp injection
Active Comparator
triple intraarticular prp injection
干预措施: prp injection (Other)
结局指标
主要结局
The Western Ontario and MacMaster Universities (WOMAC) Osteoarthritis Index
时间窗: baseline and 6 months
次要结局
- Visual Analog Scale (VAS)(baseline and 6 months)
研究者
研究点 (1)
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