NCT05313555终止不适用
The Effect of Violet Device Dosed UV-C Exposure on Healthy Hand Skin
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- Deoxyribonucleic acid (DNA) damage in the form of DNA base pair dimers measured by immunohistochemistry microscopy with statistical analysis.
研究概览
简要总结
The purpose of this trial is to determine the safety of ultraviolet light (UV-C) irradiation as a method to sanitize hands instead of chemical-based sanitizers.
Eligible participants will be enrolled and receive treatment with the Violet UV-C device or UV-B. Punch biopsies will be performed following UV exposure to quantify any changes in cellular and molecular properties of the tissue.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Good general health
- •Type 1 or type 2 skin (lightly colored skin)
- •No history of skin disorders, disease states or physical conditions which would impair evaluation of the test sites
- •Willingness and ability to follow the protocol
- •No use of lotion or hand sanitizer 3 hours before the experiment
排除标准
- •Has received an experimental drug or used an experimental device in the 30 days prior to admission to the study
- •Undergoing treatment or taking medication that increases sun sensitivity
- •History of keloids
- •History of sensitivity to lidocaine or epinephrine
- •Pregnant or nursing women, pregnancy status will be self-reported, women unsure of their pregnancy status will be excluded
研究组 & 干预措施
Ultraviolet lights (UV-B)
Active Comparator
干预措施: Ultraviolet Light (UV-B) (Device)
结局指标
主要结局
Deoxyribonucleic acid (DNA) damage in the form of DNA base pair dimers measured by immunohistochemistry microscopy with statistical analysis.
时间窗: Day 1 (visit 1 after light therapy)
次要结局
未报告次要终点
研究者
Gary Fisher
Professor
University of Michigan
研究点 (2)
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