NCT06798142进行中（未招募）不适用
Risk Stratification and Heterogeneity for Organ Damage in Acute Diquat Poisoning: A Multi-Center Cohort Study
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School1 个研究点 分布在 1 个国家目标入组 193 人开始时间: 2022年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 193
- 试验地点
- 1
- 主要终点
- Survival outcome
研究概览
简要总结
This ambispective cohort study aims to characterize the relationship between plasma diquat concentrations and organ damage risk.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •history of oral exposure to diquat solution reported by patient or proxy;
- •a specimen for the diquat plasma concentration collected immediately upon admission;
- •documentation that patients or, in case of unconsciousness of the patient, legal proxies were aware of and agreed to treatment plans.
排除标准
- •they had ingested other toxins in addition to diquat (qualitative toxicological screening tests);
- •diquat was not detected in specimens, or plasma concentration data were unavailable;
- •patients with an exposure time (time from exposure to emergency department presentation) longer than 48 hours;
- •data on organ damage were not unavailable;
- •combined with other central nervous system injuries other than toxic encephalopathy.
结局指标
主要结局
Survival outcome
时间窗: 28 days within the index date of presentation at emergency department
次要结局
未报告次要终点
研究者
Hao Sun
Principal Investigator
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
研究点 (1)
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