Study of Self-Recognition and Self/Other Distinction Disorders in Patients With Psychological Vulnerability (ALTER EGO)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 34
- 试验地点
- 2
- 主要终点
- Average of the three M1
研究概览
简要总结
The main objective of this study is to establish whether there are differences in self-recognition and self/other distinction in subjects with psychological vulnerability compared to healthy volunteer controls.
详细描述
This study is based on the properties of the double mirror "Alter Ego" which is a device that appears as a double-sided mirror surrounded by light diodes whose intensity can be varied. Thanks to this variation of luminosity, this special paradigm creates morphs between two real subjects seated on both sides, resulting in different faces, each morphed to a varying extent.
In this task, participants watch a double mirror in which a picture of their own face gradually transforms into the face of an unfamiliar other (self-to-other direction) or vice versa (other-to-self direction), and indicate at which point they judge the morph to look more like the target face than the starting face.
The comparison of the thresholds obtained by different individuals makes it possible to establish whether there could be differences between subjects with psychological vulnerability and healthy controls and to explore hypothetical links between self/other distinction abilities and symptoms of psychological vulnerability .
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 25 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Patients
Both patients and healthy volunteers arms will undergo the double mirror test within a day.
But the patients arm will additionally respond to the EASE test.
干预措施: Double mirror device ALTER-EGO (Other)
Patients
Both patients and healthy volunteers arms will undergo the double mirror test within a day.
But the patients arm will additionally respond to the EASE test.
干预措施: EASE test (Other)
Healthy volunteers
Both patients and healthy volunteers arms will undergo the double mirror test within a day.
干预措施: Double mirror device ALTER-EGO (Other)
结局指标
主要结局
Average of the three M1
时间窗: Inclusion
Average of the three M1 thresholds obtained from the "round trip" manipulation repeated three times, the M1 threshold corresponding to the level of luminosity from which a subject begins to recognize himself when his own image gradually appears (during the passage of the condition glass in mirror condition).
次要结局
- Results to tests for later prodromal symptoms(Inclusion)
- The average of the three M2(Inclusion)
- Results to tests for early prodromal symptoms assessed by EASE(xamination of Anomalous Self-Experience)(Inclusion)
- Results to tests for early prodromal symptoms assessed by SPI-A (Schizophrenia Prediction Instrument for Adults)(Inclusion)
- Results to social functioning test:(Inclusion)
- Results to tests for early prodromal symptoms assessed by PQ16 (Prodromal Questionnaire - 16)(Inclusion)
- Results to tests concerning the peculiarities of cognitive functioning (neuropsychological assessment) assessed by Wechsler scale(Inclusion)