NCT07044141进行中（未招募）1 期
Efficacy of Oral Tofacitinib in Combination With Narrow Band UVB in the Treatment of Vitiligo
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- VASI improvement upto 50%
研究概览
简要总结
20 patients will be enrolled. All were given narrowband UVB . 10 wil be give oral azathriopfine . 10 will be given tofacitinib
详细描述
Total 20 patients will be enrolled. All were given narrowband UVB . 10 wil be give oral azathriopfine 50mg twice daily. 10 will be given tofacitinib 5mg twice daily. For 6 months
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient of vitiligo with any VASI both genders 18 to 60yrs
排除标准
- •pregnancy/lactation Hyerlipidrmia Patient on immunemodulator Histry pf tuberculosis Immunocompromised patients
研究组 & 干预措施
Group A
Active Comparator
Azathioprine is an immunomodulator used in treatment of vitiligo
干预措施: Azathioprine (Drug)
Group B
Active Comparator
Tofacitinib It is a Janu kinase pathway inhibitor
干预措施: Tofacitinib (Drug)
结局指标
主要结局
VASI improvement upto 50%
时间窗: 6 months
Study will be considered efficacious if 50% improvement in VASI from baseline is seen by end of 6 months of study
次要结局
未报告次要终点
研究者
Dr ayesha wahid
Dr saadiya siddiqui
Lahore General Hospital
研究点 (1)
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