NCT05814549进行中（未招募）不适用
A Study of Using Plasma Circulating Cell Free Human Papillomavirus Deoxyribonucleic Acid to Screen (cf HPV DNA) for HPV-Related Oropharyngeal Cancer
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 9
- 试验地点
- 7
- 主要终点
- Proportion of participants found to have HPV-related OPC
研究概览
简要总结
The researchers think that a blood test (NavDx®) may be able to identify cancer early by looking for circulating DNA from Human Papillomavirus/HPV. Circulating DNA are small pieces of genes that are released into the bloodstream. The purpose of this study is to find out whether using this blood test to test for HPV DNA will help detect HPV-related Oropharyngeal Cancer/OPC.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ages 45 and older
- •Self-reported history of four or more lifetime sexual partners
- •Self-reported history of one or more lifetime oral sexual partner
- •No previous history of diagnosed HPV-related head and neck cancer
排除标准
- •History of diagnosed HPV-related OPC
- •Less than three sexual partners in lifetime
- •No history of oral sex performed
- •Younger than age 45
研究组 & 干预措施
No previous history of diagnosed HPV-related head and neck cancer
Participants have no previous history of diagnosed HPV-related head and neck cancer
干预措施: NavDx (Diagnostic Test)
结局指标
主要结局
Proportion of participants found to have HPV-related OPC
时间窗: Up to 5 years
: The primary objective is to determine the feasibility of screening by estimating the yield (proportion of subjects found to have HPV-related OPC out of all subjects screened).
次要结局
未报告次要终点
研究者
研究点 (7)
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