临床试验/NCT05814549

NCT05814549进行中（未招募）不适用

A Study of Using Plasma Circulating Cell Free Human Papillomavirus Deoxyribonucleic Acid to Screen (cf HPV DNA) for HPV-Related Oropharyngeal Cancer

Memorial Sloan Kettering Cancer Center7 个研究点分布在 1 个国家目标入组 9 人开始时间: 2023年3月31日最近更新: 2025年9月19日

适应症

试验速览

阶段: 不适用
状态: 进行中（未招募）
发起方: Memorial Sloan Kettering Cancer Center
入组人数: 9
试验地点: 7
主要终点: Proportion of participants found to have HPV-related OPC

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The researchers think that a blood test (NavDx®) may be able to identify cancer early by looking for circulating DNA from Human Papillomavirus/HPV. Circulating DNA are small pieces of genes that are released into the bloodstream. The purpose of this study is to find out whether using this blood test to test for HPV DNA will help detect HPV-related Oropharyngeal Cancer/OPC.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 45 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

•Ages 45 and older
•Self-reported history of four or more lifetime sexual partners
•Self-reported history of one or more lifetime oral sexual partner
•No previous history of diagnosed HPV-related head and neck cancer

排除标准

•History of diagnosed HPV-related OPC
•Less than three sexual partners in lifetime
•No history of oral sex performed
•Younger than age 45

结局指标

主要结局

Proportion of participants found to have HPV-related OPC

时间窗: Up to 5 years

: The primary objective is to determine the feasibility of screening by estimating the yield (proportion of subjects found to have HPV-related OPC out of all subjects screened).

次要结局

未报告次要终点

研究者

发起方

Memorial Sloan Kettering Cancer Center

申办方类型

Other

责任方

Sponsor

研究点 (7)

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