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临床试验/CTRI/2024/12/077946
CTRI/2024/12/077946尚未招募2 期

An Exploratory Study of Vishwadhya Churna in the Management of Grahani Roga

post graduate institute of ayurved jodhpur1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年12月14日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
To Assessment of Subjective and Objective Parameters Before and After Treatment

研究概览

简要总结

INTRODUCTION

Grahani is shashthi pittadharakala situated in between the stomach and the large intestine. [su.utr.40/169] Acharaya Charka says that Grahani is the seat of Agni and called so because of holding up the food. Normally, it holds up the food (until it is digested) and releases it from the side after it has been digested, but when disrupted by a sluggish digestive fire (Mandagni), the digested substance is released even in unripe conditions. This state of the working of Grahani is called Grahani Roga. [ch.chi.15/56-57] Samana Vayu, pachaka pitta and kledaka kapha are the main doshas confined to the organ Grahani. Grahani Roga is a disease of Annavaha srotas caused due to the production of Ama and Mandagni. Functionally weak agni i.e., Mandagni causes improper digestion of ingested food which leads to Grahani Roga. Due to improper digestion of food, there is vitiation of the Dosha and Agni and symptoms like alternate Constipation and Diarrhoea, with associated symptoms are seen, which can be collectively called as Grahani Roga. if left untreated Grahani Roga ensues with symptomatology like udarashoola, adhmana, arochaka, avipaka, muhurbadha muhurdrava mala pravatti, durgandhita mala pravatti, klama etc. In the present era, GrahaniRoga is a common GI tract disorder affecting daily life because of its direct link with improper food habits and stressful lifestyle. Globally prevalence of Grahani about (11.2%) and Indian prevalence is (4.2- 7.7%).

METHOD OF PREPARATION OF TRIAL DRUG

All the herbal drugs will be collected in their proper collecting time and in dry forms. All these dried herbal ingredients will be taken in equal quantity. Then all the dried herbs will be grinded very finely, filtered with a cotton cloth and mixed with each other thoroughly. Drugs will be prepared in pharmacy of University College of Ayurveda Jodhpur.

研究设计

研究类型
Interventional
分配方式
Other
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patients having age between 18-70 years of either sex presenting with clinical features of Grahani Roga Patient willing to sign the consent form Patients having symptoms of Grahani Roga.

排除标准

  • Pregnant women and lactating mothers.
  • Mixed infections with parasites such as round worms, hook worms etc.
  • Infectious disorders like intestinal tuberculosis.
  • Patients with bleeding per rectum.
  • Abuse of drug or alcohol.

结局指标

主要结局

To Assessment of Subjective and Objective Parameters Before and After Treatment

时间窗: 60 Days

次要结局

  • To observe any side effects if occur during clinical trial(60 Days)

研究者

发起方
post graduate institute of ayurved jodhpur
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Nisha Kumari Meena

post graduate institute of ayurved, jodhpur

研究点 (1)

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