Most Effective Stimulation Site in Transcranial Direct Current Stimulation for Gait Recovery After Stoke
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Changes in motor evoked potential
研究概览
简要总结
The aim of this study is to investigate the most effective stimulation site in transcranial direct current stimulation for gait recovery after stroke. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) bihemispheric stimulation - anodal stimulation on both ipsilesional and contralesional leg area of primary motor cortex and supplementary motor area. 2) ipsilesional stimulation - anodal stimulation on ipsilesional leg area of primary motor cortex and supplementary motor area. 3) contralesional stimulation - anodal stimulation on contralesional leg area of primary motor cortex and supplementary motor area. 4) sham stimulation. Subjects will walk on treadmill for 10 minutes during transcranial direct current stimulation. Motor evoked potential and functional evaluations will be done before and after stimulation to measure the changes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Chronic stroke patients with 6 months after onset.
- •Functional ambulation category ≥ 3
排除标准
- •patients who needs assist in surface level walking
- •patients with mini mental status exam score under 9
- •patients with implantable electronic device
- •metal device inside skull
- •history of epilepsy
- •pregnancy
结局指标
主要结局
Changes in motor evoked potential
时间窗: before and after intervention (approximately 30 minutes)
measure the motor threshold and amplitude of motor evoked potential in tibialis anterior muscle.
次要结局
- Changes in 10 meter walking test(before and after intervention (approximately 30 minutes))
- Timed up and go test(before and after intervention (approximately 30 minutes))
- Changes in Fugl Meyer Assessment(before and after intervention (approximately 30 minutes))
- Functional ambulatory category(before and after intervention (approximately 30 minutes))
- Changes in motricity index(before and after intervention (approximately 30 minutes))
- Modified ashworth scale(before and after intervention (approximately 30 minutes))