Comparison Effects of Negative Calorie Diet and Low-calorie Diet on Weight Loss and Lipid Profile in Sedentary Overweight/Obese Middle-aged and Older Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 37
- 主要终点
- Weight
研究概览
简要总结
Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method. The present study aimed to determine the effects of negative-calorie diet on weight loss and lipid profile, and to compare its efficiency with low-calorie diet.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 75 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Non-smokers and weight-stable (± 2 kg, for more than one year) with no history of regular exercise in at least three months before the study.
排除标准
- •History of CVD and other disorders such as diabetes, depression, eating disorders, chronic medications, kidney disease, cancer, food allergies or intolerances to items used in meals.
- •Subjects with abnormality in thyroid or Electrocardiograph, any history of anti-obesity medication or weight loss drugs or dietary supplementations for weight control.
研究组 & 干预措施
Study group I
Study group I (19 participants) received the NCD (details of diet: 15% protein, 75% carbohydrates, 10% fat). Both groups had 15% caloric restriction from their maintenance energy requirements.
干预措施: NCD (Dietary Supplement)
Study group II
Study group II (18 participants) received the LCD or healthy weight maintenance diet (details of diet: 15% protein, 55% carbohydrates, 30% fat).Both groups had 15% caloric restriction from their maintenance energy requirements.
干预措施: LCD (Dietary Supplement)
结局指标
主要结局
Weight
时间窗: pre-study
assessed in kg
Total cholesterol (Total-C)
时间窗: pre-study
assessed in mg/dl
High-density lipoprotein -cholesterol (HDL-C)
时间窗: pre-study
assessed in mg/dl
Low-density lipoprotein -cholesterol (LDL-C)
时间窗: pre-study
assessed in mg/dl
Triglycerides (TG)
时间窗: pre-study
assessed in mg/dl
次要结局
- Total cholesterol (Total-C)(3-month)
- Weight(3-month)
- High-density lipoprotein -cholesterol (HDL-C)(3-month)
- Low-density lipoprotein -cholesterol (LDL-C)(3-month)
研究者
Mohammadreza Rezaeipour, MD, PhD
Assistant professor of sports medicine (sports injury and corrective movement)
University of Sistan and Baluchestan