Cloxacillin as Prevention of Double Lumen Infection in Hemodialysis Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- catheter infection
研究概览
简要总结
The purpose of this study is to investigate whether cloxacillin lock is effective in prevention of double lumen infection.
详细描述
Double lumen infection is one of the causes of morbidity and mortality in hemodialysis patients. Many strategies used to prevent it and one of them is antibiotic lock. Thus we select chronic hemodialysis patients and divided them into 2 groups. One group received cloxacillin and heparin as catheter lock and the second group received only heparin lock.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •hemodialysis for 3 months
- •at least 2 time dialysis/week
排除标准
- •active infection
- •acute renal failure
研究组 & 干预措施
1
cloxacillin 100 mg/ml + heparin 1000iu/ml as catheter lock at the end of hemodialysis
干预措施: cloxacillin (Drug)
1
cloxacillin 100 mg/ml + heparin 1000iu/ml as catheter lock at the end of hemodialysis
干预措施: heparin (Drug)
2
heparin 1000iu/ml as catheter lock at the end of hemodialysis
干预措施: heparin (Drug)
结局指标
主要结局
catheter infection
时间窗: 6 months
次要结局
未报告次要终点