Presurgical Evaluation of Nonmelanoma Skin Cancers Using High Frequency Ultrasound
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Complete excision of nonmelanoma skin cancers
研究概览
简要总结
- To ensure complete elimination of lesions with maximum preservation of function and aesthetics.
- To elaborate the Ultrasonographic features of skin cancers.
- To determine the accuracy of HIFU to assess the margins of skin lesions and its safety margins by histopathiological examination..
- To follow up the patient postoperatively for incomplete excision or recurrence by clinical and HIFU examination.
详细描述
The skin is the most superficial and largest body organ, due to its function as a surface covering for the body, enables the performance of noninvasive diagnostic and investigative procedures.
Of all the tumors that affect humans, non-melanoma cutaneous cancer is the most common e.g. basal cell carcinoma (BCC) and squamous cell carcinoma (SCC).
Techniques such as high frequency ultrasound (HFUS) enable the real-time study of cutaneous lesions, making them excellent pre-operative tools varying considerably in their penetration, resolution, and applicability.
High frequency ultrasound has been used in dermatology since the 1970s, ultrasonography is a painless non-radioactive imaging diagnostic method based on the reflection of sound waves through body tissues.
High frequency ultrasound allows for the delimiting of the margins of the neoplasia, due to the difference in echogenicity between the hypoechoic tumoral area and the hyperechoic perilesional area.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients between 30 & 80 years.
- •Lesions clinically apparent locally malignant, or malignant.
- •Lesions with or without visible ulcerations.
排除标准
- •Surgeon unable to visualize tumor on clinical examination.
- •Patients unfit for surgery.
结局指标
主要结局
Complete excision of nonmelanoma skin cancers
时间窗: Baseline
Determination the accuracy of HIFU to assess the margins of skin lesions and its safety margins to ensure complete elimination of lesions with maximum preservation of function and aesthetics
次要结局
未报告次要终点
研究者
George Gamil Gergis
Doctor
Assiut University