Effects of Home-based Inspiratory Muscle Training in Patients With Idiopathic Pulmonary Fibrosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 2
- 主要终点
- Change in inspiratory muscle strength
研究概览
简要总结
The aim of this study is to investigate the effects of the home-based inspiratory muscle training program on lung functions, dyspnea, inspiratory muscle strength, functional capacity and quality of life in patients with idiopathic pulmonary fibrosis. Patients are evaluated before the inspiratory muscle training and after 8 weeks of training.
详细描述
The IMT protocol consisted of home-based high-intensity daily training - two cycles of 30 breaths with a 1-min rest between sets, twice a day for 8 weeks using an IMT Threshold device (Threshold IMT Philips® Respironics, Inc). The intensity of the training was set to 50% of each patient's maximal inspiratory pressure measured every week and was adjusted weekly based on the modified Borg scale from 4 to 6 regarding respiratory effort performed during the session. Patients are evaluated before the inspiratory muscle training and after 8 weeks of training.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosing Idiopathic Pulmonary Fibrosis by a pulmonologist;
- •Aged between 40 and 75 years;
- •Volunteering to research;
- •Stable clinical condition (same medication routine and/or no acute exacerbation in the last for the last 4 weeks).
排除标准
- •Inability of the participant to understand or perform the procedures proposed during the evaluations or training program.
- •Participating in any pulmonary rehabilitation programs;
- •A previous pneumonectomy or lobectomy operation;
- •Pneumonia in the last 4 weeks;
- •Any pulmonary infection during the study;
- •Requirement for supplemental oxygen therapy while resting.
- •Having Covid-19 disease (during the study or in the past)
- •Orthopaedic or neurological conditions affecting the ability to independent walking
结局指标
主要结局
Change in inspiratory muscle strength
时间窗: 8 weeks
MIP
次要结局
- Change in Dyspnea(8 weeks)
- Change in percentages of forced vital capacity(8 weeks)
- Change in diffusing capacity of the lung for carbon monoxide(8 weeks)
- Change in Functional capacity(8 weeks)
- Change in percentages of forced expiratory volume in one second(8 weeks)
研究者
Ridvan Aktan
Principal Investigator, PhD
Izmir University of Economics