NCT00522028已完成不适用
Asymptomatic Primary Hyperparathyroidism: A Prospective, Randomized Trial
Oslo University Hospital1 个研究点 分布在 1 个国家目标入组 191 人开始时间: 1998年10月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 191
- 试验地点
- 1
研究概览
简要总结
The present study is a randomized, controlled trial that investigates the effects of parathyroidectomy or medical observation in mild asymptomatic pHPT on morbidity and quality of life (QoL).
详细描述
The patients are included and randomized by block randomization to medical observation or parathyroidectomy by an experienced parathyroid surgeon.
The patients will be followed up for 10 years.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Untreated, asymptomatic pHPT
- •2.60>S-Ca<2.85 mmol/liter
- •Age between 50 and 80 yr
- •No medications interfering with Ca-metabolism
- •Informed consent
排除标准
- •Hyperparathyroid bone disease
- •Previous operation in the neck
- •Impaired kidney function
- •Kidney stones
- •Complicating medical conditions
- •Psychiatric disorders
- •Multiple endocrine neoplasia,
- •Familial hypocalcuric hypercalcemia
- •Familial HPT
研究者
Jens Bollerslev
Professor
Oslo University Hospital
研究点 (1)
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