A Prospective Multicenter Phase II Study of MabThera (Rituximab) Plus 2 Weekly CHOP Followed by Low Dose Total Body Irradiation in Elderly Patients With Diffuse Large B-Cell Lymphoma

University of Aarhus0 个研究点目标入组 40 人开始时间: 2003年1月最近更新: 2009年2月3日

适应症

试验速览

阶段: 2 期
状态: 已完成
发起方: University of Aarhus
入组人数: 40

研究概览研究设计入排标准研究者记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to determine whether the application of low dose total body irradiation following chemo-immuntherapy in elderly patients with aggressive with non-Hodgkin's lymphoma would be safe and potentially benecicial adjuvant therapy

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Treatment
盲法: None

入排标准

年龄范围: 60 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•previously untreated, pathology verified aggressive non-Hodgkin lymphoma of the diffuse large B-cell type according to the WHO classification. Age between 60 years and 80 years.Positive for an anti-CD20 antibody. Good performance status and normal initial normal blood count.

排除标准

•Patients with previous lymphoma associated with immune suppression of any sort. Diagnosis or history of indolent lymphoma or other malignancies. Marked impairment of any vital organ such as the heart, lung, liver or kidneys.

研究者

发起方

University of Aarhus

申办方类型

Other

相似试验

已完成

2 期

Study Assessing the Potential for Reduced Rates of Implant Failure Using Multi-Beam Intensity-Modulated Radiation Therapy for Locally Advanced Breast Cancer Patients With Implant ReconstructionsBreast Cancer

NCT02086578Memorial Sloan Kettering Cancer Center100

已完成

2 期

Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell TransplantationMyelodysplastic SyndromesMyeloproliferative DisorderAcute Myeloid LeukemiaChronic Lymphocytic LeukemiaT-cell LymphomaNon Hodgkin LymphomaB-cell LymphomaHodgkin LymphomaChronic Myelomonocytic Leukemia

NCT03734601Stanford University22

终止

2 期

Low-Dose Radiation Therapy to the Whole Liver With Gemcitabine and Cisplatin in IHCIntrahepatic Cholangiocarcinoma

NCT02254681Allina Health System6

招募中

不适用

The GOAL27-6 StudyHead and Neck Cancer

NCT05859828East and North Hertfordshire NHS Trust60

Unknown

2 期

Bevacizumab and Radiotherapy for Oligometastasis of Lung Adenocarcinoma With Negative Driver GeneLung Adenocarcinoma

NCT03905317Sun Yat-sen University66