Frequency of Wound Dehiscence and Wound Infection in Continuous Versus Interrupted Suturing for Abdominal Closure in Exploratory Laparotomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Wound Dehiscence
研究概览
简要总结
The goal of this clinical trial is to learn whether the type of suturing technique used to close the abdomen after exploratory laparotomy affects the rate of wound complications. Specifically, the study aims to find out if using interrupted sutures results in fewer cases of wound dehiscence (wound reopening) compared to continuous sutures.
The main question the study seeks to answer is:
Does interrupted suturing reduce the frequency of wound dehiscence compared to continuous suturing in patients undergoing exploratory laparotomy?
Researchers will also observe and compare wound infection rates between the two suturing methods.
About 80 adult patients (18-60 years old) undergoing exploratory laparotomy at the Department of General Surgery, DHQ Teaching Hospital, Dera Ghazi Khan, will take part in this study. Participants will be randomly assigned to one of two groups:
Group A: Continuous abdominal closure using No. 1 Vicryl suture
Group B: Interrupted abdominal closure using No. 1 Vicryl suture
All participants will have their baseline characteristics recorded, including age, gender, obesity, diabetes, and smoking status. The surgical technique and postoperative care will follow the hospital's standard protocols. After surgery, patients will be followed for four weeks with weekly clinical assessments to check for wound infection or wound dehiscence.
The hypothesis is that patients whose abdominal wounds are closed with interrupted sutures will have a lower frequency of wound dehiscence compared to those with continuous sutures.
The findings will help guide surgeons on which abdominal closure method provides better wound healing and fewer postoperative complications.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Undergoing exploratory laparotomy
- •Both emergency and elective
排除标准
- •Patients undergoing second laparotomy or re- laparotomy
- •Patients on steroid therapy (assessed on medical record review)
- •Patients who die within 28-days of surgery
结局指标
主要结局
Wound Dehiscence
时间窗: From enrollment to 28-days of operation
A partial or total separation of previously approximated wound edges, on clinical examination of surgical wound.
次要结局
未报告次要终点
研究者
Muhammad Shehroz Sarwar
Principal Investigator
Allama Iqbal Teaching Hospital
