TCTR20200710001招募中1 期
Efficacy and safety of 0.15% Thiamidol combination with hyaluronic acid versus 0.15%Thiamidol or hyaluronic acid alone in treatment of melasma : A randomized single-blind trial
Faculty of medicine, Thammasat university0 个研究点目标入组 96 人开始时间: 2020年7月10日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 96
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- Female
入选标准
- •1.Women 18-65 years of age having general good health
- •2.Fitzpatrick skin type II-IV
- •3.Individuals with any types of melasma
- •4.Individuals who use sunscreen daily with at least SPF30
- •5.Individuals that willing to provide written informed consent and are able to read, speak, write, and understand Thai.
- •6.Individuals of child-bearing potential who are willing to take a urine pregnancy test prior to study enrollment and when deemed appropriate by the investigator and/or sponsor
- •7. Individuals of child-bearing potential who use an acceptable method of contraception throughout the study and must be on a stable use for 3 months prior to study enrollment and must not alter their use, including dose or regimen for the duration of the study
- •8. Willing to withhold all facial treatments during the course of the study, including botulinum toxin, injectable fillers, microdermabrasions, intense pulse light, peels, laser treatment and thread
- •9. Willing to co-operate and participate by following study requirements for the duration of the study and to report any changes in health status or medications, adverse event symptoms, or reactions immediately
排除标准
- •1. History of laser resurfacing procedures, deep skin peel,
- •botulinum toxin, or injection with a dermal filler, or
- •cosmetic procedures on the face within 6 months prior to
- •enrollment.
- •2. Use of depigmenting products within 2 months prior to
- •enrollment.
- •3. Use of any topical medications on the face for the
- •treatment of hyperpigmented lesions or other conditions,
- •or use of photosensitizing medication or procedures,
- •bleaching products on the face, UV light therapy, topical
- •prescription treatments, transamin, glutathione, vitamin or topical tretinoin on the face, or Use of acitretin, isotretinoin, systemic retinoids, methotrexate, or photoallergic, phototoxic, or photo-sensitizing drugs fewer than 30 days prior to the study entry.
- •4. Facial microdermabrasion treatment within 6 weeks
- •prior to study entry.
- •5. Known allergies to facial skin care products.
- •6. Pregnancy or nursing or planning to become pregnant
- •during the study according to subject self-report,
- •including those who are not using an acceptable
- •method of contraception throughout the study.
- •7. History of skin cancer.
- •8. A health condition and/or pre-existing or dormant
- •dermatologic disease on the face (e.g., psoriasis, rosacea,
- •acne, eczema, seborrheic dermatitis, severe excoriations)
- •that the investigator deems inappropriate for participation
- •or could interfere with the outcome of the study.
- •9. History of immunosuppression/immune deficiency disorders, including HIV infection or acquired immunedeficiency syndrome, or currently using immunosup-
- •pressive medications and/or radiation as determined by study
- •documentation.
- •10. Uncontrolled disease such as asthma, diabetes, hyper-
- •tension, hyperthyroidism, or hypothyroidism. Individuals
- •having multiple health conditions may be excluded from
- •participation even if the conditions are controlled by diet
- •or medication.
研究者
相似试验
已完成
不适用
Evaluation of a new substance (isobutylamido thiazolyl resorcinolcream) compared to the use of hydroquinone 4% cream to treat facial blemishesMelasmaRBR-87kphyFaculdade de Medicina de Botucatu (FMB - Unesp)
尚未招募
4 期
sefulness of Timolol in a condition of vascular overgrowth of tissueCTRI/2019/04/018581Indian Association of Dermatologists Venereologists and Leprologists Research grant
招募中
3 期
The efficacy and safety of 0.5% topical timolol on corneometry and transepidermal water loss after ablative fractional CO2 laser for atrophic acne scars: a split face randomized double blind placebo-controlled trialWe considered that timolol may have an effect in wound healing promotion in patients who undergo AFCO2 resurfacing. Our study aimed to investigate the efficacy and safety of 0.5% topical timolol maleaTCTR20190722005none25
尚未招募
3 期
se of medicines- Hydroxyurea and thalidomide for children suffering from thalassemiaCTRI/2023/12/060945ICMR, Delhi
尚未招募
Unknown
To compare the effectiveness of Thiamine in combination with Vitamin C and itâ??s combination with Glutamine on survival outcome in critically ill patients admitted in ICCTRI/2023/03/050828Manjeeta Kumari