JPRN-UMIN000006174已完成未知
Goal-Oriented Therapy Evaluated By Cardiopulmonary Exercise Testing For Pulmonary Arterial Hypertension - GOOD EYE
Department of Cardiology, Nagoya University Graduate School of Medicine0 个研究点目标入组 129 人开始时间: 2011年8月15日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 129
研究概览
简要总结
The primary endpoint was cardiovascular death. In the goal-oriented therapy group, plasma brain natriuretic peptide, mean pulmonary arterial pressure, pulmonary vascular resistance, and 6-min walk test were significantly improved at 12 months compared with baseline. Survival in the goal-oriented therapy group at 1, 2, and 3 years (97.6%, 95.2%, and 86.0%, respectively) tended to be higher than that in the conventional empiric therapy group (P=0.082).
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 16years-old 至 80years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) Pulmonary hypertension due to left heart disease, Pulmonary hypertension due to lung diseases and/or hypoxia, Chronic thromboembolic pulmonary hypertension 2) Pregnant 3) Moderate or severe hepatic failure patients 4) More than 2.0 mg/dl Serum creatinine levels 5) Severe interstitial lung disease 6) Coronary artery disease 7) The patients can not walk by themself. 8) The patients who have taken medications for PAH treatment drugs including the pill PGI2, endothelin receptor antagonists, phosphoesterase inhibitors-5, and intravenous epoprostenol 9) Inappropriate patients due to other reasons
研究者
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