Pilot Study to Evaluate Ear Acupressure Effects in Treating Seasonal Allergic Rhinitis
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 18
- 试验地点
- 2
- 主要终点
- Rhinoconjunctivitis Quality of Life Questionnaire (Nasal Symptoms Domain Only)
研究概览
简要总结
We hypothesize that ear acupressure will be effective in treating seasonal allergic rhinitis by changing the immune parameters and the psychological impact factors are associated with ear acupressure treatment outcome.
详细描述
The purpose of the study is to investigate the clinical potential of ear acupressure in treating seasonal allergic rhinitis. We hypothesize that ear acupressure will be effective in treating seasonal allergic rhinitis by changing the immune parameters and the psychological impact factors such as expectation, stress, depression, and anxiety can moderate the ear acupressure treatment effectiveness in allergic rhinitis by influencing the immune parameters.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Seasonal allergic rhinitis was diagnosed both by history and clinical examination and by the presence at positive skin prick tests
- •All participants need to have at least 2 years of seasonal allergic rhinitis symptoms and a positive skin prick test to one or more pollen allergens
排除标准
- •use of systemic corticosteroids within past 3 months period,
- •active asthma,
- •hearing aid usage,
- •history of adhesive tape allergy,
- •history of metal allergy,
- •hepatitis B or C,
- •history of hematologic, autoimmune, or malignant disease,
- •pregnancy or lactation,
- •ear acupressure (EAP) or acupuncture for respiratory disease within the last 6 months
结局指标
主要结局
Rhinoconjunctivitis Quality of Life Questionnaire (Nasal Symptoms Domain Only)
时间窗: 8 weeks
RQLQ is an instrument that has 28 items in 7 domains (sleep, non-rhinoconjuctivitis symptoms, practical problems, nasal symptoms, eye symptoms activity limitations and emotional function). Participants are asked to recall impairments experienced during the previous week and to respond to each item on a 7-point scale (0=no impairment; 6=maximum impairment). In this protocol, we used the nasal symptoms domain only; 4 questions, total scale ranges from 0 minimum to 24 maximum. Longitudinal changes of nasal symptoms domain total were reported from baseline to 8 weeks.
次要结局
- Psychological Measures(8 weeks)
研究者
Gailen D. Marshall Jr., MD PhD
Professor of Medicine and Pediatrics, Vice Chair for Research, Department of Medicine, Director, Division of Clinical Immunology and Allergy, Chief, Laboratory of Behavioral Immunology Research
University of Mississippi Medical Center